She has extensive experience in analyzing large datasets using a broad range of statistical analyses, including large genetically informative data such as inflammatory biomarkers. Inga Schwabe (MTO) is an expert in the field of longitudinal data analyses and statistical genetics. She is the current project coordinator of the Brabant Study, a large population-cohort of mothers and their children who are followed from pregnancy onwards. Brucie (Scottish origin) means forest fairy. Alvin (Swedish origin) means noble friend. Alston (British origin) means elf stone or noble stone. Boekhorst has extensive experience in large-scale data collection and implementation. Alberich (German origin) means ruler of supernatural beings (elves). The Tooth Fairy now has her own phone number to congratulate kids on losing teeth and encourage them to care for their smiles helping to promote good oral. Myrthe Boekhorst (MCP) studies psychological maternal wellbeing during pregnancy (e.g., stress, depression, mindfulness). TOOTH FAIRY DENTAL LAB LTD - Free company information from Companies House including registered office address, filing history, accounts, annual return. Van den Heuvel has experience with deciduous teeth research in the PELS study for which she is the principal investigator. The Virtual ToothFairy video chats with children to tell them about why. She examines how these prenatal and early life influences (e.g., maternal prenatal stress and anxiety) can impact brain development. The Virtual ToothFairy promotes healthy teeth and choices for children ages 4-10. van den Heuvel (CNP) is an expert in early neurobiological influences of early child development. As such, this project is an important steppingstone for relevant research into the effect of maternal stress on child development outcomes. Using teeth biomarkers as alternative indicator for maternal stress enables the identification of critical periods of maternal stressors that influence healthy lifespan trajectories. And that is what we focus on in this project: Identifying a teeth biomarker of maternal stress during pregnancy by retrospectively examining deciduous teeth that have been shed in early childhood (between the ages of 6 to 12). While this novel discovery offers a non-invasive, direct measure of maternal stress exposure during pregnancy (intensity and timing), assessing stress markers in deciduous teeth have yet to be validated in-depth. Recent developments in quantitative molecular imaging have made it possible to use them to identify prenatal and postnatal stress marker. We propose an innovative solution for this problem: using deciduous teeth (baby teeth) biomarkers as an alternative indicator for maternal stress exposure.ĭeciduous teeth, hidden in the gum of a developing fetus, can be seen as biological hard drives: they “store” exposure data from the 14 th week of pregnancy onwards. Research into the effect of exposure to maternal stress during pregnancy on child developmental outcomes can take years to collect.
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